منابع مشابه
Chromatin-associated Proteins in Cultured Human Cells
(2000) The proliferation-specific human Ki-67 protein is a constituent of compact chromatin. (2001) The human origin recognition complex protein 1 dissociates from chromatin during S-phase in HeLa cells.
متن کاملCarcinogen metabolism in cultured human tissues and cells.
A large number of chemical carcinogens require metabolic activation before they are biologically active. The metabolism of a few of these compounds has been investigated in cultured human tissues and cells and the metabolism has been compared with the metabolism in organs from experimental animals in which the compounds induce cancer. Generally, only quantitative differences could be observed b...
متن کاملAsynchronous Dna Synthesis of Sex Chromatin in Human Interphase Nuclei
The sex chromatin body is an oval or round chromatin mass approximately 1 micron in diameter lying against the inner portion of the nuclear membrane. In human tissue it is present in about 20 to 40 per cent of female cells and is absent in male cells. The sex chromatin of somatic interphase nuclei is thought to be derived from a portion of a single heteropyknotic X chromosome (1, 2). Lima-de-Fa...
متن کاملUridine-5-h3 Radioautography of the Human Sex Chromatin Body
To obtain an estimate of the rate of RNA synthesis by the heterochromatic sex chromatin body, human female fibroblasts were labeled with uridine-5-H(3) and radioautographed. The number of grains over the sex chromatin body was compared with the number of grains over a comparable area of euchromatin. The ratio was 0.37. When corrected for the higher content of DNA per unit area in heterochromati...
متن کاملChromatin immunoprecipitation on native chromatin from cells and tissues (PROT22)
In cells and tissues, the histone proteins that constitute the nucleosomes can present multiple post-translational modifications (Luger & Richmond, 1998), such as lysine acetylation, lysine and arginine methylation, serine phosphorylation, and lysine ubiquitination. On their own, or in combination, these covalent modifications on the core histones are thought to play essential roles in chromati...
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ژورنال
عنوان ژورنال: Nature
سال: 1959
ISSN: 0028-0836,1476-4687
DOI: 10.1038/184477a0